Yes and no. If you want to make screen printed transfers for a cold peel application, you can use almost any standard plastisol ink. This is assuming that the plastisol ink that you want to use has a formulation that has enough opacity to give you a acceptable print result. Cold peel transfers have a thicker, rubbery feel that is O.K. for substrates like ball caps or non-apparel items like pennants, flags, etc. But cold peel transfers are less than ideal for t-shirts or other wearables because of the heavy ink deposit that many people find objectionable.
If you want a "direct screen printed" look with a "soft hand" feel, you will need to use a specially formulated hot split transfer plastisol ink.
When applying a heat transfer using transfers printed with hot split plastisol ink, a portion of the ink remains on the paper and the remainder is transferred to the garment--thus the name the "hot-split." Hot split plastisol inks come in regular opacity as well as high opacity formulations.
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